Research 

First Psychedelic Clinical Trial in Chile

The ECOH Foundation will conduct the first psychedelic clinical research in Chile in the last 50 years. This clinical and neuroscientific investigation consists of a pilot study for the treatment of Major Depression through psilocybin-assisted therapy (the active compound found in hallucinogenic mushrooms). The research is led by Dr. Constanza Baquedano (Foundation Vicepresident and Secretary), along with Dr. Christopher Timmermann (Foundation President), Dr. Pilar del Río (Clinical Director of the Foundation), Dr. Enzo Tagliazucchi (Foundation collaborator), and Dr. Rodrigo Figueroa (Foundation collaborator). If you wish to contribute with the project, please contact us.

Members of the ECOH foundation have performed world-leading scientific research in psychedelics, meditation, and consciousness in the fields of neuroscience, psychology, psychiatry, philosophy, and sociology

Dr. Christopher Timmermann

Christopher is the director of the DMT Research Group at Imperial College London, UK. His interdisciplinary work focuses on the neuroscience, psychiatry, psychology, and beliefs of psychedelics, their relationship to consciousness and applications in mental health. The work he has led has been published in high-impact journals, and has been widely covered by media outlets such as the BBC, The Guardian, The Times, WIRED, and CBC.

For the ECOH Foundation he investigates overlaps of different non-ordinary states of consciousness, as well as the introduction of psychedelic therapy and research in Chie. In addition to being the president of ECOH Foundation he is also a member of the multi-disciplinary organizations ALIUS (France), EPRC (USA) and DICTA Foundation (Chile).

Dr. Constanza Baquedano

Currently, Constanza is an associate lecturer at Universidad Adolfo Ibañez (Chile). Constanza investigates the use of meditation and other contemplative states using a neurophenomenological approach including quantitative, behavioural and qualitative measures and is leading the design for the first clinical trial involving psilocybin for treatment resistant depression.

For the ECOH Foundation, she studies “expanded” states of human consciousness associated with mental health and as well as improved ecological awareness. In addition to being the vice-president of the ECOH Foundation, she is president of the Resiliencia Andina Foundation (dedicated to the conservation of mountain ecosystems) and a member of the Mind and Life Institute.

Mg. Cristóbal Dañobeitia

Cristobal studies the impact of scientific and religious arguments on social orientation and the use of phenomenological methods to describe decision-making. Following an internship at Ecole Normale Supérieure, he specialised in the elicitation interview method. Returning to Chile, he founded Embodied Reports, integrating phenomenological principles with motion sensors to evaluate audiovisual and musical content.

At ECOH, he researches the public perception of psychedelics, and how the phenomenology of imagery and music influences our understanding of ‘consciousness.’ Besides his ECOH role, he directs Embodied Reports and presides over the Chilean Music Digital Observatory, aiming to create an online system for decision-making in the music industry.

Dr. Fernando Rosas

His PhD thesis was focused in the analysis of telecommunication networks, a topic which drove him into statistical physics and complex systems theory. Previously, he has worked as a Postdoctoral researcher at the Department of Electrical Engineering of KU Leuven, Research Fellow at the Department of Electrical Engineering of National Taiwan University, and Marie Curie Research Fellow at the Department of Mathematics and Department of Electrical Engineering at Imperial College London.

He works as an associate lecturer at the University of Sussex and is an honorary researcher at the Centre for Psychedelic Research and the Data Science Institute at Imperial College London. He currently works on developing novel quantitative methods for the study of altered states of consciousness, with a special interest in the role of collective dynamics and the interface between science and arts.

Dra. Catherine Andreu

She conducted her doctoral thesis at the Psychophysiology Laboratory under the guidance of Diego Cosmelli and Ingmar Franken, where she investigated the effect of mindfulness practice on cognitive control using electro-physiological measures. She was the recipient of the Francisco Varela Award from Mind and Life Europe and worked as a postdoctoral researcher at the Millennium Institute for Research in Depression and Personality (Chile), studying the effects of a mindfulness-based intervention on the executive function of schoolchildren in a vulnerable context in Chile.

Currently, she serves as a postdoctoral researcher at the Universitat de Valencia as a María Zambrano Fellow. Her current research focuses on the effects of mindfulness-based interventions and compassion-based interventions on psychobiological measures

Dr. Josefina Cruzat

Her research aims to characterise the fundamental biophysical mechanisms and principles that underlie different healthy brain states and understand how they are affected in neuropsychiatric diseases and altered states of consciousness. She integrates large-scale mathematical models with advanced analysis methods applied to multimodal neuroimaging, neurophysiology, and neuropsychology data. Her approach will help identify and link brain states—in terms of neural network dynamics—with mental states, offering new biomarkers for diagnosis and enabling the development of novel therapeutic interventions to treat dysfunctional mental states.

Josefina is currently a researcher at the Latin American Brain Health Institute (BrainLat) of the Adolfo Ibañez University.

Dr. Aurelio Riquelme

He currently works as a psychiatrist at San Borja Arriaran Hospital (Chile). His main interests are: the relationship between non-ordinary states of consciousness and positive behavioural changes, as well as the effects of meditation, states of flow, near-death experience and phenomena associated with mystical experiences.

Dr. Rodrigo Cofré

He completed his PhD thesis in the Neuromathcomp (INRIA Sophia-Antipolis) team, supervised by Prof. Bruno Cessac where he studied mathematical modelling in neuroscience, focusing on the visual sensory system. He held a postdoctoral position in the Department of Theoretical Physics, University of Geneva, Switzerland (supervised by Prof. J.-P Eckmann). He is currently a joint Professor at the Institute of Mathematical Engineering at Universidad de Valparaíso, where his main research interests include modelling complex systems, computational neuroscience, and non-ordinary states of consciousness.

In addition to being a member of EcoH, he is the director of the research group Brain-Information-Complexity Laboratory (Brincolab).

Dr. Rubén Herzog

For his doctoral thesis he investigated the biophysical mechanisms involved in the effect of psychedelic compounds in the human brain using mathematical-computational models of neuronal dynamics.

For the ECOH Foundation, he investigates different epistemological and biological perspectives to account for the complexity of non-ordinary states of consciousness, as well as delivering a wide set of mathematical and computational tools for the analysis of biological data. He is part of several international collaborations investigating neural mechanisms involved in different states of consciousness using whole-brain models and information theory.

Dr. Felipe Landaeta

Felipe completed his PhD thesis at CIIS, which consisted on the interpretive phenomenological analysis of the perceived impact of Holotropic Breathwork in a Chilean sample. He works as an assistant professor at the U. Adolfo Ibáñez and as a psychotherapist. Since 2010 he has run Holotropic Breathwork sessions, working with more than 1000 people to date.

He has a special interest in investigating the therapeutic potential of non-ordinary states of consciousness and developing research on the effects in mental health of Holotropic Breathwork.

Ps. Santiago Valdivieso

Currently he works as a Transpersonal Psychotherapist, providing therapeutic accompaniment in the preparation and integration of non-ordinary states of consciousness.

His interest is to continue developing a methodological framework for ethical, psychotherapeutic work with non-ordinary states of consciousness, and supporting scientific research for the validation of the therapeutic potential for the clinical use of psychedelics in Chile.

Dr. Francisco Carrera

He currently works as a Clinical Psychiatrist at the Public Health System in Chile. He is a member of the Asociación de Profesionales ELAM-Chile, a non-profit medical organization, which provides service for populations in the context of natural disasters within national territory. He has experience clinically advising substance users at Fundación Latinoamérica Reforma (Chile), in the context of Law 20,000, which sanctions drug users.

His interests at the ECOH Foundation are to lay the foundations so that in the future psychedelic substances are used as a tool for psychiatric clinical work in Chile. Together with the team, he aims to develop clinical studies associated with non-ordinary states of consciousness, for the treatment of different mental disorders, as well as for human development.

Dr. Emilio Bravo Mendoza

At the ECOH Foundation he is interested in the generation of scientific evidence on the therapeutic use of psychedelics and other non-ordinary states of consciousness for psychiatric pathologies, and for the improvement of psychological well-being in general. He is also interested in the dialogue between psychedelics and compassion. Finally, he wishes to educate about the therapeutic and responsible use of psychedelics in Chile.